Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley +1 more source
Assessment of the impact of post-processing approaches on absolute myocardial blood flow quantification using cardiac-dedicated CZT-SPECT: A retrospective observational study. [PDF]
Shi Y +5 more
europepmc +1 more source
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Triple-Tracer Sentinel Node Mapping: Maximizing Detection, Minimizing Dissection. [PDF]
Cristian DA +8 more
europepmc +1 more source
Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces
Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein +6 more
wiley +1 more source
Successful revascularization of chronic total renal artery occlusion in a young patient with resistant hypertension and renal dysfunction: a case report. [PDF]
Cenelı D +4 more
europepmc +1 more source
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu +11 more
wiley +1 more source
THE PREPARATION OF TECHNETIUM METAL
openaire +3 more sources
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng +13 more
wiley +1 more source
Successful GH Treatment of Hepatopulmonary Syndrome in Panhypopituitarism-related Advanced Liver Disease. [PDF]
Chen S +5 more
europepmc +1 more source

