Results 191 to 200 of about 2,627,818 (309)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
A Metafrontier Analysis of Technical Efficiency of Selected European Agricultures
Technical efficiency refers to the situation where it is impossible for a firm to produce, with the given know-how, (1) a larger output from the same inputs or (2) the same output with less of one or more inputs without increasing the amount of other ...
Revoredo-Giha, Cesar, Barnes, Andrew P.
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, 1990 Made available in DSpace on 2009-03-30T17:16:19Z (GMT). No. of bitstreams: 3 inhscaev01990i00009_tei.xml: 123969 bytes, checksum: 1165d99e95850998c69ba029cda418fe (MD5) inhscaev01990i00009_opt.pdf: 1316224 bytes, checksum ...
Bayley, Peter B. +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
TECHNICAL EFFICIENCY OF GRAIN PRODUCTION IN UKRAINE
A stochastic grain production frontier model is estimated on a representative sample of Ukrainian state farms. Technical inefficiency effects are modeled as a function of workforce composition, other farm-specific variables, and time.
Jensen, Helen H., Kurkalova, Lyubov A.
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DETERMINANTS OF TECHNICAL EFFICIENCY IN AGRICULTURE AND CATTLE RANCHING: A SPATIAL ANALYSIS FOR THE BRAZILIAN AMAZON [PDF]
The determinants of technical efficiency in agriculture and cattle ranching are closely related with the debate involving the conservation-development trade-off in the Brazilian Amazon. Concerned with balancing development and environmental conservation,
Danilo Camargo Igliori
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2011 The project aims to improve both research capacity for the staff of the Economic Department of the Office of the National Assembly, and build the skills needed to use research information and evidence for members of the Assembly, strengthening the ...
Centre for Analysis and Forecasting
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
A behavioral view of the head-and-shoulders technical analysis pattern
, 2010 The technical analysis approach to predicting stock returns is based on the identification of recurrent patterns in the way stock prices evolve in time, (a) using optical examination of price history, and (b) a host of technical indicators.
Tsinaslanidis, P., Zapranis, A.
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