Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
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Effect of using a mobile phone on technical efficiency and productivity of climate-smart horticulture farmers in Taita-Taveta county, Kenya. [PDF]
Mwikamba JN, Otieno DJ, Oluoch-Kosura W.
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Acute effects of motor learning models on technical efficiency in strength-coordination exercises: a comparative analysis of Olympic snatch biomechanics in beginners. [PDF]
Ammar A +4 more
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Technical efficiency of teff farms in Ethiopia: Do neighborhood effects matter? A copula stochastic frontier and spatial Durbin regression. [PDF]
Fikadu AA, Gebre GG.
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Technical efficiency of Fishers under the condition of water hyacinth infestation: Evidence from Lake Tana fisheries, Ethiopia. [PDF]
Asmare E, Aragaw Y.
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A Stochastic Frontier Approach to Study the Relationship between the Hygienic Quality of Bulk Tank Sheep Milk and Technical Efficiency of the Coagulation Process. [PDF]
Jiménez L +7 more
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Level of technical efficiency and associated factors among health centers in East Gojjam Zone, Northwest Ethiopia: an application of the data envelopment analysis. [PDF]
Lamesgen A +3 more
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Technical efficiency and its determinants in health service delivery of public health centers in East Wollega Zone, Oromia Regional State, Ethiopia: Two-stage data envelope analysis. [PDF]
Geta ET +7 more
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Measuring Technical Efficiency and Productivity of Secondary Maternal and Child Health Hospitals in Hubei, China: Some Evidences from Hubei Province of China 2019 to 2021. [PDF]
Cheng J, Jia C, Zhang Y, Zhu Y, Wang Q.
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Jens Leth Hougaard
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