Results 81 to 90 of about 6,118,389 (306)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Multiobjective optimization of technical market indicators

, 2009
This paper deals with the optimization of technical indicators for stock market investment. Price prediction is a problem of great complexity and usually some technical indicators are used to predict the markets trends.
Hidalgo, José Ignacio, Bodas, Diego, Fernández, Pablo, Risco, José Luis, Soltero, Francisco, J. Ignacio Hidalgo, Francisco J. Soltero, Diego J. Bodas-Sagi, Pablo Fernández, José L. Risco-Martín   +9 more
core   +1 more source

Prediction of the Stock Market Using a Hybrid Model Based on Feature Expansion and LSTM-Based Algorithms

IEEE Access
The complexity associated with predicting stock market trends has garnered significant attention from researchers and financial analysts. The widespread use of the stock market as an investment platform by individuals accentuates the importance of ...
B. Swetha, Kriti Arya
doaj   +1 more source

Penalized logistic regressions with technical indicators predict up and down trends. [PDF]

Soft comput, 2022
Jiang H, Hu X, Jia H.
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Towards New Technical Indicators for Trading Systems and Risk Management [PDF]

We derive two new technical indicators for trading systems and risk management. They stem from trends in time series, the existence of which has been recently mathematically demonstrated by the same authors (A mathematical proof of the existence of ...
Michel Fliess, Cédric Join
core  

An Adaptive Modality Fusion Network for Stock Trend Prediction

IEEE Access
Financial markets are increasingly shaped by structured indicators and unstructured news flows, making trend prediction a multimodal challenge under uncertainty.
Khalid Bentaleb, Mohamed Ben Houad, Mohammed Mestari   +2 more
doaj   +1 more source

Application of Artificial Neural Networks in Stock Market Timing: A Technical Analysis Approach [PDF]

پژوهشهای اقتصادی, 2008
Stock market timing is a very difficult task because of the complexity of the market. Since there are various factors affecting the market and therefore it is not a simple task to predict future stock price and its trend.
Reza Tehrani, Vahid Abbasion
doaj