Results 191 to 200 of about 5,887,141 (213)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Unilateral cleft lip repair - A technical note

SRM Journal of Research in Dental Sciences, 2010
Kamal K Kannadasan, M V Sainath, S Nabeel   +2 more
doaj  

From medical student to Editor: A note of thanks

Ca-A Cancer Journal for Clinicians, 2023
Ted Gansler
exaly  

Birmingham Intervention Tent Technique (BITT): A Technical Note

Indian Journal of Radiology and Imaging, 2021
Rajesh Botchu, S L James
exaly  

A New Application of Gelatin Sponge in the Treatment of Hemifacial Spasm by Microvascular Decompression: A Technical Note

Journal of Neurological Surgery, Part A: Central European Neurosurgery, 2022
Shiting Li, Bowen Chang, Xiangyu Wei
exaly  

EUCAST Technical Note on Voriconazole and Aspergillus spp.

Clinical Microbiology and Infection, 2013
Cornelia Lass-Florl, M C Arendrup, M Cuenca-Estrella   +2 more
exaly  

EUCAST technical note on anidulafungin

Clinical Microbiology and Infection, 2011
William Hope, M Cuenca-Estrella, M C Arendrup   +2 more
exaly  

EUCAST Technical note on Amphotericin B

Clinical Microbiology and Infection, 2011
William Hope, Cornelia Lass-Florl, M C Arendrup   +2 more
exaly