Results 61 to 70 of about 471,332 (214)
Fronthaul-Constrained Cloud Radio Access Networks: Insights and Challenges
, 2015 As a promising paradigm for fifth generation (5G) wireless communication systems, cloud radio access networks (C-RANs) have been shown to reduce both capital and operating expenditures, as well as to provide high spectral efficiency (SE) and energy ...
Lau, V., Peng, M., Poor, H. V., Wang, C.
core +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Thermal Management Technologies for Space Data Centers： Current Status and Prospects
Zhileng xuebaoSignificanceThe rapid expansion of artificial intelligence， large satellite constellations， and deep-space exploration is reshaping global demand for computing infrastructure.
Shi Jiahao +3 more
doaj
Automatic differentiation in machine learning: a survey [PDF]
, 2018 Derivatives, mostly in the form of gradients and Hessians, are ubiquitous in machine learning. Automatic differentiation (AD), also called algorithmic differentiation or simply "autodiff", is a family of techniques similar to but more general than ...
Baydin, Atilim Gunes +3 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A Taxonomy of Workflow Management Systems for Grid Computing
, 2005 With the advent of Grid and application technologies, scientists and engineers are building more and more complex applications to manage and process large data sets, and execute scientific experiments on distributed resources.
A. Geppert +12 more
core +4 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Small-world networks, distributed hash tables and the e-resource discovery problem [PDF]
, 2010 Resource discovery is one of the most important underpinning problems behind producing a scalable, robust and efficient global infrastructure for e-Science.
Hawick, K.A., Leist, A.
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Інноваційні моделі навчання і підготовки кадрів для індустрії високих технологій в Україні [PDF]
, 2013 The problems of development of innovative learning environment of continuous education and training of skilled personnel for high-tech industry are described.
Биков, В.Ю. +1 more
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