Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Flow Patterns Around a Sphere in Terms of Wall Proximity
Flow over a sphere exhibits three-dimensional phenomena even at lower values of Reynolds number (Re). Nonetheless, three-dimensional flow structures may also be affected by boundary layers on the rough walls.
İlker Göktepeli +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Technogenic Risk, Reliability and Diagnostics of Technical Systems: Approaches, Models, Methods
An interpenetrating character of concepts «reliability», «safety», and «risk» in the general structure of the concepts defining quality of technical system is demonstrated.
N.A. Makhutov +3 more
doaj
Science in the muslim world: contribution of UTM scientist [PDF]
Nowadays, there are many products and technologies that have been contributed by scientists all over the world. Thus, this paper is emphasized more on the contribution of the Muslim scientists in Universiti Teknologi Malaysia (UTM) which an innovation ...
Alias, Norul Aina +2 more
core
Thermographic non-destructive evaluation for natural fiber-reinforced composite laminates [PDF]
Natural fibers, including mineral and plant fibers, are increasingly used for polymer composite materials due to their low environmental impact. In this paper, thermographic non-destructive inspection techniques were used to evaluate and characterize ...
Avdelidis, Nicolas P. +7 more
core +3 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Scientific Support of the Energy-Intensive Technologies Modernization in Mechanical Engineering
This article summarizes the experience of the Joint Institute of Mechanical Engineering of the NAS of Belarus on the organization of scientific support for the Technical re-equipment and modernization of the foundry, thermal, galvanic, and other energy ...
P.A. Vityaz, A.A. Djuzhev , A.A. Shipko
doaj
Optimization of chemical composition in the manufacturing process of flotation balls based on intelligent soft sensing [PDF]
This paper presents an application of computational intelligence in modeling and optimization of parameters of two related production processes - ore flotation and production of balls for ore flotation.
Dučić Nedeljko +4 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

