Results 51 to 60 of about 15,653,086 (211)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A SUGGESTED PROCEDURE FOR TESTING LARGE CASSEGRAIN OPTICAL SYSTEMS
QC 351 A7 no. 43The optical elements of a cassegrain telescope are commonly tested individually, with their axes in a horizontal position. When these optical elements are inserted in the telescope, the resulting imagery is often dis- appointing.
Lytle, John D.
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
QC 351 A7 no. 19ABSTRACT The classical properties of an image formed by an optical system looking through a turbulent medium are scintillation, agitation, and blur.
Shack, R. V.
core
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
ELECTROENCEPHALOGRAPHIC CORRELATES OF VISUAL STIMULUS CHARACTERISTICS AND DECISION CERTAINTY
QC 351 A7 no. 84The problem: to what extent do cortical evoked potentials correlate with differences in complex visual stimuli and with differences in observer confidence that a correct judgment has been made?
Wheeler, L., Yee, B., Seeley, G. W.
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A PUPIL COATING FOR QUASI-PERFECT IMAGE FORMATION
QC 351 A7 no. 21It is found that, despite the finite extent of any real pupil, an absorption coating exists which, when applied to the pupil of an optical system, results in nearly perfect formation of the coherent image.
Frieden, B. Roy
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
TWO-SURFACE OPTICAL SYSTEMS WITH ZERO THIRD-ORDER SPHERICAL ABERRATION
QC 351 A7 no. 37This paper derives four one-parameter families of two-surface optical systems having the property that, relative to a well-defined pair of conjugate points, one finite and the other infinite, third-order spherical aberration is zero.
Stavroudis, O. N.
core

