Results 61 to 70 of about 388,542 (358)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Don Reitz: Out of the Ashes [PDF]
The writer discusses the work of ceramic sculptor Don Reitz on the occasion of an exhibition of his work at the Natalie and James Thompson Art Gallery at San Jose State University in San Jose, California, from October 28 to December 19, 2008.
Hernandez, Jo Farb
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Magnified Clam Image Captures Top Award in NOAA Photo Contest [PDF]
Aquatic Diagnostic Technician Kathryn Markey Lundgren’s carefully constructed image of a tiny Northern quahog wins first place in National Oceanic and Atmospheric Administration’s aquaculture photo ...
Polin, Sabrina
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Barnes Hospital Bulletin [PDF]
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1085/thumbnail ...
core +4 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
LATE DIAGNOSIS OF HEREDITARY HEMORRHEGIC TELANGIECTASIA
Introduction: Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant vascular disease with an average prevalence of 1 in 5000-8000 inhabitants. It is caused by an alteration in angiogenesis that leads to vascular alterations.
NLL Dornelles +3 more
doaj +1 more source
Poster Panel: The Collection [PDF]
This poster panel was part of the Dr. Jane Claire Dirks-Edmunds exhibit that was on display at Linfield College\u27s Jereld R. Nicholson Library in April and May of 2015.
Hilton, Samantha Noelle
core +1 more source

