Results 71 to 80 of about 388,542 (358)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
On some tree species, annual sprays may control western poplar clearwing moth
California Agriculture, 1994 The western poplar clearwing moth, a serious pest to many species of western ornamental trees, can cause limb breakage or tree death in severe cases.
Walter Bentley +2 more
doaj +1 more source
A voice-actuated wind tunnel model leak checking system [PDF]
A voice-actuated wind tunnel model leak checking system was developed. The system uses a voice recognition and response unit to interact with the technician along with a graphics terminal to provide the technician with visual feedback while checking a ...
Larson, W. E.
core +1 more source
Hester Prynne, Lydia Bennet, and Section 306 Stock: The Concept of Tainting in the American Novel, the British Novel, and the Internal Revenue Code [PDF]
, 2001 Did Nathaniel Hawthorne\u27s novel, The Scarlet Letter, inspire Section 306 of the Internal Revenue Code? This code provision adopts a peculiarly Hawthorne-like solution to a tax avoidance scheme known as the preferred stock bailout. Section 306 taints
Cohen, Stephen B, Cohen, Stephen B.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Kelola: Jurnal Manajemen Pendidikan, 2020 The objective of this research is to evaluate the context, input, process and product components in Evaluating Implementation of Competency Test Place for Automotive Technician at SMK Negeri 2 Salatiga.
Sartono Manto Suwarno, Bambang Ismanto
doaj
Jurnal Kesehatan Lingkungan, 2019 Aviation is the most significant part of Indonesian Air Force duty. Air Force’s aircraft takes a role not only as Indonesian army agency transportation vehicle but also crucial for Indonesian air territory security protection. However the level of noises
ristyna choirunisa
doaj +1 more source