Results 81 to 90 of about 295,920 (304)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Development and Application of Lightweight High-strength Metal Materials

MATEC Web of Conferences, 2018
This article reviews the performance, alloy composition and the development of advanced lightweight high-strength materials such as high-strength steels, high-strength aluminum alloys, high-strength magnesium alloys, and titanium alloys.
Pan He
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Effects of VR technical interaction and acceptance on rural cultural identity: The mediating role of embodied cognition and flow experience

Telematics and Informatics Reports
With the development of digital media, an increasing number of new technologies are being used in cultural communication, and virtual reality (VR) technology for cultural communication has become a modern tool of transmission.
Xiuyu Lin, Yating Wang, Zehui Zhan, Qin Wang, Dongmei Xiang, Huiyan Li   +5 more
doaj   +1 more source

Research on taking the road of Chinese path to modernization well——Based on a new development perspective [PDF]

SHS Web of Conferences
The fact of the matter is that Chinese modernization is not only a great creation of CPC, but also a path we must take to realize the rejuvenation of the Chinese nation.
Yang Gu, Hua Liu
doaj   +1 more source

A voice-actuated wind tunnel model leak checking system [PDF]

A voice-actuated wind tunnel model leak checking system was developed. The system uses a voice recognition and response unit to interact with the technician along with a graphics terminal to provide the technician with visual feedback while checking a ...
Larson, W. E.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Internet treatment for generalized anxiety disorder: a randomized controlled trial comparing clinician vs. technician assistance.

PLoS ONE, 2010
BackgroundInternet-based cognitive behavioural therapy (iCBT) for generalized anxiety disorder (GAD) has been shown to be effective when guided by a clinician.
Emma Robinson, Nickolai Titov, Gavin Andrews, Karen McIntyre, Genevieve Schwencke, Karen Solley   +5 more
doaj   +1 more source

Transactions of the Institute of British Surgical Technicians (Incorporated) 6, Holborn Viaduct, E.C.1 [PDF]

, 1940

openalex   +1 more source