Results 171 to 180 of about 12,307,103 (335)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Pancreatic transplantation using duct occlusion technique [PDF]
Abendroth, D. +3 more
core +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Reduced Fascial Dehiscence with Combined Small-and-Large Technique Compared to Small-Bite Technique in Emergency Midline Laparotomy: A Retrospective Study. [PDF]
Koca F +6 more
europepmc +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Ipsilateral pull-through technique using a handmade loop snare catheter for difficult port catheter removal. [PDF]
Matsuo T +4 more
europepmc +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Application of Double-Colored Die-Stone as an Alternative Approach for Achieving Superior Finish Line Precision in Dental Casts: A Comparative In Vitro Study. [PDF]
Toumaj A +6 more
europepmc +1 more source
Heat Transfer and Fluid Control Techniques in Space Machinery
Shintaroh Enya +3 more
openalex +2 more sources

