Results 41 to 50 of about 2,829,438 (266)

Computing techniques

open access: yesCoRR, 2020
This lecture aims at providing a user's perspective on the main concepts used nowadays for the implementation of numerical algorithm on common computing architecture. In particular, the concepts and applications of Central Processing Units (CPUs), vectorisation, multithreading, hyperthreading and Graphical Processing Units (GPUs), as well as computer ...
openaire   +2 more sources

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Single-shot impulsive stimulated Brillouin microscopy by tailored ultrashort pulses

open access: yesJournal of the European Optical Society-Rapid Publications
Brillouin microscopy has become an important tool for investigating the mechanical properties of tissue. The recently developed Impulsive Stimulated Brillouin Scattering (ISBS) promises a label-free, non-invasive measurements of viscoelastic properties ...
Krause David   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Distribution of 226Ra and 210Po Radionuclides in Different Phases of Soil and Estimation of Their Annual Change Rates for Some Agricultural Soils

open access: yesApplied and Environmental Soil Science
Human activities, such as plant cultivation, enhance the activity concentrations (ACs) of radionuclides in the topsoil and have the potential to affect humans and the environment.
Van Thang Nguyen, Cong Hao Le
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
In this study, a series of 4,5-bis(substituted phenyl)-4H-1,2,4-triazol-3-amine compounds was designed, synthesised, and evaluated to determine their potential as anti-lung cancer agents.
Xian-yu Sun   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Extraction Method for Multiple Feature Models of the Magnetic Field from Marine Targets

open access: yes水下无人系统学报
Maritime targets cause distortions in the surrounding magnetic field, forming the target’s magnetic field signature. This signature is widely used in target detection and ship stealth. To address the issue of multi-modal feature extraction for the target’
Hao DONG, Yu ZHANG, Wei QIN, Shuai CHEN
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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