Results 71 to 80 of about 10,817,841 (245)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Data fusion for timber bundle volume measurement

, 2019
In many industrial fields, the direct measurement of a specific parameter of interest can be too costly to be feasible. Using data from other parameters about the process, a data driven approach can instead be used for a cost-efficient estimation of the ...
Liguori C., O'Nils M., Pietrosanto A., Carratu M., Lundgren J.   +4 more
core   +1 more source

JUMP LANDING MECHANICS OF ADOLESCENT ATHLETES DURING AGES OF PEAK ACL INJURY RISK: IDENTIFYING SEX DIFFERENCES WITH A PORTABLE MOTION SENSOR

Orthopaedic Journal of Sports Medicine, 2019
Background: Anterior cruciate ligament (ACL) injury rates in adolescent female athletes are 3x greater than males, with peak incidence at 16 and 17 years of age for girls and boys, respectively.
Brad W. Willis PT, MPT, Seth Sherman, Trevor Gulbrandsen MD, Scott M. Miller MD, Nathan Siesener MD, Trent M. Guess PhD, Kyle Blecha ATC, Zhiyu Huo MS, Marjorie Skubic PhD, Aaron D. Gray MD   +9 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Measures Vs. Actions: The Balanced Scorecard in Swedish Law Enforcement [PDF]

(WP 12/03 Clave pdf) Our investigation drew upon the deployment of the balanced scorecard in Swedish Law Enforcement, an organization that long ago implemented the new paradigm of policing, which consisted in enhancing the quality of urban life on the ...
SALVADOR CARMONA
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Intelligent denoiser of plasma waves by SS-520-3 sounding rocket experiment toward future EMC challenges in miniaturized platform chassis

Earth, Planets and Space
Electromagnetic compatibility (EMC) is a standard test to ensure that electromagnetic instruments used in scientific experiments, such as those on spacecraft, CubeSats, and sounding rockets, operate without causing interference.
Mitsunori Ozaki, Ray Morita, Akihiro Hirano, Satoshi Yagitani, Yoshiya Kasahara, Takahiro Zushi, Satoshi Kurita, Hirotsugu Kojima   +7 more
doaj   +1 more source

Interchangeability of Cross-Platform Orthophotographic and LiDAR Data in DeepLabV3+-Based Land Cover Classification Method

Land
Riverine environmental information includes important data to collect, and the data collection still requires personnel’s field surveys. These on-site tasks still face significant limitations (i.e., hard or danger to entry).
Shijun Pan, Keisuke Yoshida, Satoshi Nishiyama, Takashi Kojima, Yutaro Hashimoto   +4 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source