Results 161 to 170 of about 382,611 (265)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

AI and Robotics Advancement in Analytical Mineral Characterization and Mining Processes: A Review and Research Trends Analysis. [PDF]

open access: yesTop Curr Chem (Cham)
Mkhohlakali A   +11 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Comparison of tissue acquisition techniques for Next-Generation Sequencing of non-small cell lung cancer (NSCLC). [PDF]

open access: yesBMJ Open Respir Res
Bhamani A   +12 more
europepmc   +1 more source

Robust Pre-processing Technique Based on Saliency Detection for Content Based Image Retrieval Systems

open access: diamond, 2016
Chesti Altaff Hussain   +2 more
openalex   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Large-area 3D reconstruction of corneal tissues from oscillating focus confocal microscopy. [PDF]

open access: yesSci Rep
Allgeier S   +7 more
europepmc   +1 more source

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