Results 291 to 300 of about 19,717,505 (344)

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source
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Managing the development of large software systems: concepts and techniques

International Conference on Software Engineering, 2021
INTRODUCTION l am going to describe my pe,-.~onal views about managing large software developments. I have had various assignments during the past nit,.: years, mostly concerned with the development of software packages for spacecraft mission planning ...
W. Royce
semanticscholar   +1 more source

Basics of Qualitative Research (3rd ed.): Techniques and Procedures for Developing Grounded Theory

, 2008
Introduction -- Practical considerations -- Prelude to analysis -- Strategies for qualitative data analysis -- Introduction to context, process and theoretical integration -- Memos and diagrams -- Theoretical sampling -- Analyzing data for concepts ...
J. Corbin, A. Strauss
semanticscholar   +1 more source

Basics of qualitative research: Grounded theory procedures and techniques.

, 1992
Introduction Getting Started Theoretical Sensitivity The Uses of Literature Open Coding Techniques for Enhancing Theoretical Sensitivity Axial Coding Selective Coding Process The Conditional Matrix Theoretical Sampling Memos and Diagrams Writing Theses ...
A. Strauss, J. Corbin
semanticscholar   +1 more source

Techniques

Current Opinion in Microbiology, 2009
The past century of microbiological research has produced an impressive understanding of microbial diversity, relevance, and basic metabolism. As a crowning symbol of this progress, today the complete genome sequences of nearly 1000 different bacterial species are available and can be automatically annotated (approximately) and mapped onto metabolic ...
Garin, Jérôme, Jensen, Grant J.
openaire   +3 more sources

A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects.

, 1969
With the vast research interest in sleep and dreams that has developed in the past 15 years, there is increasing evidence of noncomparibility of scoring of nocturnal electroencephalograph-electroculograph records from different laboratories.
E. Wolpert
semanticscholar   +1 more source

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