Results 31 to 40 of about 511 (262)

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

TRADICIONESCULTURALESAFROCUBANASENELBARRIOÁFRICADE YAGUAJAY/AFRO-CUBAN CULTURAL TRADITIONS IN THE AFRICA NEIGHBORHOOD IN YAGUAJAY

Pedagogía y Sociedad, 2020
Introducción: En Cuba se han desarrollado proyectos comunitarios que promueven las expresiones del arte, pero aún existen dificultades en cuanto a reconocer y practicar uno de los fenómenos culturales que caracterizan al pueblo de Yaguajay desde su ...
Ivania García-Viamonte, Anna Lidia Beltrán-Marín, José Camilo Valdivia-Cruz   +2 more
doaj  

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

Modo de Vida de un grupo de trabajadores informales, Bogotá D.C., 2014

Revista Facultad Nacional de Salud Pública, 2016
Resumen Objetivo: Comprender el modo de vida de un grupo de trabajadores informales vendedores de productos agrícolas en carreta, en el territorio de Corabastos, Bogotá D.C., como aproximación al perfil epidemiológico del grupo.
Ana H. Puerto G, Pablo E. Torres A, Felipe A. Roa G, Jhon E. Hernández C   +3 more
doaj   +1 more source

Differentiated Impacts of EU Rural Development Measures: A Finite Mixture Evaluation of Italian Olive Farms

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper examines the relationship between participation in the EU Rural Development Program and the economic performance of Italian olive farms using a finite‐mixture model with inverse‐probability‐weighted regression adjustment. Based on 2010–2022 FADN panel data, it estimates heterogeneous treatment effects while correcting for selection ...
Francesco Caracciolo, Marilena Furno
wiley   +1 more source

Voluntary Collective Action to Address Growing Agricultural Challenges in Two Countries: Experimental Insights and Commonalities

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT We conducted two framed field economic experiments with citrus farmers in Florida, United States and soybean farmers in Argentina to investigate their willingness to coordinate pest and weed management efforts. Despite the contrast between these two agricultural contexts, we find striking behavioral commonalities.
Ariel Singerman, Sergio H. Lence
wiley   +1 more source

Hacia una reconstitución de los procedimientos artísticos magdalenienses: contribución del análisis microscópico en el campo del arte mueble

Trabajos de Prehistoria, 1997
[es] A partir del postulado de que el proceso de realización de un objeto del arte mueble magdaleniense tiene una cierta tradición técnica que puede expresar valores cognitivos y culturales, este trabajo se orienta hacia la percepción de las técnicas de ...
Carole Fritz
doaj   +1 more source

Ex‐Ante Assessment of Farm Resilience to Institutional Shocks: A Modeling Approach

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Using the agent‐based model SWISSland, we simulate farm‐level responses and interactions under two institutional shocks: tariff reductions and direct payment reductions. Using a framework we developed, we assess resilience capacities, resilience attributes, and the provision of private and public goods, following the shock.
Nadja El Benni, Gabriele Mack
wiley   +1 more source

L’impact de l’alphabétisation en langue locale en Côte d’Ivoire [PDF]

Akofena
L’engagement du gouvernement dans l’alphabétisation en langues nationales à travers le projet école intégrée (PEI) et l’initiative ELAN (école et langue nationale) montre d’emblée l’importance de cet enseignement.
GUESSAN née DRI Lou Claudine
doaj   +1 more source