Safety and efficacy of a feed additive consisting of <i>Lactococcus lactis</i>DSM 34262 as an acidity regulator additive for all animal species (Lactosan GmbH & Co.KG). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
europepmc +1 more source
Advanced Additive Remanufacturing Technology
Sheng Zhu +5 more
openaire +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Rapid Detection of Plasticizer Migration From UV-Aged PVC Films by DART-HRMS. [PDF]
Leite-Barbosa O +4 more
europepmc +1 more source
STUDY ON INVESTMENT NEEDS AND OBSTACLES ALONG INDUSTRIAL VALUE CHAINS. April 2017 [PDF]
Esteves, Sofia +6 more
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Safety of a feed additive consisting of zeolites (≥ 50%) obtained from Neapolitan Yellow Tufa for poultry for fattening or reared for laying/reproduction (Italiana Zeoliti s.r.l.). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +20 more
europepmc +1 more source
Additive Manufacturing Technology
openaire +2 more sources
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source

