Results 291 to 300 of about 182,310 (338)

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Physical activity substitution: An overlooked constraint on energy expenditure during exercise and physical activity interventions. [PDF]

Diabetes Obes Metab
Thompson D, Del Angel M, Nunes MA, Gonzalez JT, Betts JA, Peacock OJ.   +5 more
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Assessment of the feed additive consisting of Lactiplantibacillus plantarumCECT 4528 for all animal species for the renewal of its authorisation (Centro Sperimentale del Latte S.r.l.). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Anguita M, Bozzi Cionci N, Brozzi R, Innocenti ML, Valeri P, García-Cazorla Y.   +22 more
europepmc   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Assessment of the feed additive consisting of Pediococcus acidilactici NCIMB 30005 for all animal species for the renewal of its authorisation (Microferm ltd.). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Anguita M, Bozzi Cionci N, Galobart J, Innocenti ML, Revez J.   +21 more
europepmc   +1 more source

Effects of Fungal Probiotics on Rumen Fermentation and Microbiota in Angus Cattle. [PDF]

Animals (Basel)
Wang L, Li M, Liu C, Li X, Wang P, Chang J, Jin S, Yin Q, Zhu Q, Dang X, Lu F.   +10 more
europepmc   +1 more source

Safety and efficacy of a feed additive consisting of Kieselguhr (diatomaceous earth) for all animal species (Imerys France). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Bampidis V, Dierick N, Woutersen R, de Lourdes Bastos M, Ramos F, Galobart J, Vettori MV, Holczknecht O, Ortuño J, Pizzo F, Valeri P, Innocenti ML, Amaduzzi A.   +29 more
europepmc   +1 more source

Influence of 3D Printing Parameters on the Mechanical Properties for Numerical Simulation of the Poly (Lactic Acid). [PDF]

Polymers (Basel)
Catana DI, Brus DI, Pop MA, Luca MA.
europepmc   +1 more source

INFLUENCE OF SUPERPLASTIFYING ADDITIVES BASED ON POLYCARBOXYLATE ETHER ON THE TECHNOLOGICAL AND PHYSICAL-TECHNICAL PROPERTIES OF GYPSUM-CETMENT-POZZOLANIC BINDER

H. A. Qais, R. Bogdanov, N. N. Morozova, Azat Mavlyuberdinov, Lyudmila Suleymanova   +4 more
openalex   +1 more source