Results 41 to 50 of about 74,032 (309)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Энергетические характеристики топлив и способы их определения
Известия высших учебных заведений: Проблемы энергетики, 2017 Chemical energies and exergies reflect more correctly and completely the energy potentials of fuels than the calorimetric values that generally used in practical calculations.
doaj +1 more source
Annals of West University of Timisoara: Physics, 2020 Ab initio calculations of BiFeO3 magnetic perovskite are carried. Accurate density functional theory calculations were performed considering a U-Hubbard correction (DFT+U) to account for on-site Coulomb interactions of the 3d-Fe states.
Derras M., Hamdad N.
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Games, 2020 In this paper, we develop a new dynamic model of optimal investments in R&D and manufacturing for a technological leader competing with a large number of identical followers on the market of a technological product. The model is formulated in the form of
Sergey M. Aseev, Masakazu Katsumoto
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2021 Present study offers great prospects for the adsorption of anti-inflammatory celecoxib molecule (CXB) over the surface of zinc oxide (Zn12O12) and magnesium oxide (Mg12O12) nanoclusters in several environments by performing robust theoretical ...
Ng Kay Lup, Andrew +12 more
core +1 more source
THE APPLICATION OF SOFTWARE "FARMEKSPERT SERVICE" FOR COST-EFFECTIVENESS ANALYSIS
Medična Informatika ta Inženerìâ, 2012 The article aduces the main stages of pharmacoeconomic calculations to establish the size of the labour costs of employees’ pharmacies military medical service.
R. L. Prytula +8 more
doaj +1 more source
The improvement in technology of rectification column calculation
IOP Conference Series: Earth and Environmental Science, 2020 Abstract The task of automation and increasing the efficiency of calculating the parameters of the rectifying column for the needs of chemical production is being solved. Rectification is one of the most time-consuming chemical-technological processes responsible for the separation of liquid mixtures into practically pure components ...
A A Popov +4 more
openaire +1 more source