Managing the interface between public sector applied research and technological development in the Chinese enterprise sector [PDF]
China's technological capabilities are emerging rapidly and the country will become a major challenger to established nations in terms of R&D and innovation in the near future.
Schiller, Daniel, Kroll, Henning
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
TECHNOLOGICAL COLLABORATION: BRIDGING THE INNOVATION GAP BETWEEN SMALL AND LARGE FIRMS [PDF]
This paper analyses technological collaboration as an input to the innovation processes of SMEs. Technological collaboration may be a useful mechanism to offset some of the weaknesses in SMEs’ resource endowments and bring their innovation capabilities ...
Maria Jesus Nieto, Lluis Santamaria
core +2 more sources
Dynamic Capabilities and their Indirect Impact on Firm Performance [PDF]
This paper investigates the relationship between dynamic capabilities and firm performance. In particular it addresses the question of whether dynamic capabilities impact directly or indirectly on performance.
Spyros Lioukas +2 more
core
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
What do we really know about when technological innovation improves performance (and when it does not)? [PDF]
Most approaches to innovation bear the implicit assumption that increased innovativeness leads to improved organizational performance. Thus, more attention has been focused on innovativeness than on innovation performance; on novelty than on value ...
Adegbesan, Tunji, Ricart, Joan E.
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Foreign Direct Investment, Firm-Level Capabilities and Human Capital Development: Evidence from Kenyan Manufacturing Industry [PDF]
This paper uses firm-level survey data of Kenyan manufacturing industry to examine the significance of FDI and firm-level capabilities in human capital development.
Gachino, Geoffrey
core
How does absorptive capacity influence the origin and evolution of dynamic capabilities [PDF]
, 2010 In this thesis, I deploy a qualitative case-study method to examine the influence of a firm’s absorptive capacity of external knowledge on the origin and evolution of dynamic capabilities.
Lawer, Christopher
core
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source