Results 41 to 50 of about 142,381 (311)
Cooperation for innovation in developing countries and its effects: evidence from Ecuador
Journal of Technology Management & Innovation, 2017 This paper evaluates the impact of the most common innovation linkages by type of innovation activity on firms’ innovation inputs and outputs. In order to estimate the casual effects, we employ Inverse Probability Weighting, while focusing on exclusive ...
Juan Fernández Sastre +1 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Ownership, technological capabilities and exports of garment firms in Myanmar
Technological and Economic Development of Economy, 2014 This paper uses the evolutionary framework to examine the relationship between ownership, technological capabilities and export intensities using garment manufacturing in the Least Developed Country of Myanmar as an empirical case.
Rajah Rasiah, Myo Myo Myint
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Driver machine-tool adaptations and its technological capabilities [PDF]
Научно-технический вестник Брянского государственного университета, 2016 The article presents the design of the driver machine-tool adaptations based on rigid and floating center for machine tools of the turning group, as well as their technological capabilities in providing quality workpieces.
Erokhin V.V.
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Path of the Formation and Evolution of Technological Capabilities for Manufacturing Complex Product Systems in Latecomer Firms: The Case Study of TUGA Company [PDF]
بهبود مدیریت, 2018 During last decades a large amount of efforts have been made by developing countries to acquire essential knowledge and technological capabilities for manufacturing and developing complex products systems (CoPS). As an example, TUGA as an Iranian company
Mostafa Safdari +3 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source