Results 41 to 50 of about 7,793,316 (286)

Recent Advances in Amorphous Solid Dispersions: Preformulation, Formulation Strategies, Technological Advancements and Characterization

open access: yesPharmaceutics, 2022
Amorphous solid dispersions (ASDs) are among the most popular and widely studied solubility enhancement techniques. Since their inception in the early 1960s, the formulation development of ASDs has undergone tremendous progress.
S. Tambe   +8 more
semanticscholar   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Technological characterization of vaginal probiotic lactobacilli: resistance to osmotic stress and strains compatibility

open access: yesJournal of Applied Microbiology, 2019
The aim was to evaluate the osmotic stress resistance of vaginal beneficial probiotic strains, their growth kinetics and parameters when growing in salt‐added culture media, and their compatibility to go further in the design of a probiotic formula for ...
J. A. Silva   +3 more
semanticscholar   +1 more source

Winemaking structure in Brazil. Technological Characterization

open access: yesLes territoires de la vigne et du vin au Brésil, 2020
Au Brésil, l'élaboration de vins fins en volumes importants est un phénomène de moins d'un siècle qui a progressivement évolué vers la situation actuelle, avec une certaine diversité des types et des styles.
Celito Crivellaro Guerra   +1 more
semanticscholar   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Isolation, technological characterization and in vitro probiotic evaluation of Lactococcus strains from traditional Turkish skin bag Tulum cheeses

open access: yesAnnals of Microbiology, 2019
The present study was undertaken to evaluate in vitro prerequisite probiotic and technological characteristics of ten Lactococcus strains isolated from traditional goat skin bags of Tulum cheeses from the Central Taurus mountain range in Turkey.
Erhan Kazancıgil   +3 more
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A Characterization of Generator and Component Reuse Technologies [PDF]

open access: yes, 2001
This paper characterizes various categories of reuse technologies in terms of their underlying architectures, the kinds of problems that they handle well, and the kinds of problems that they do not handle well. In the end, it describes their operational envelopes and niches. The emphasis is on generative reuse technologies.
openaire   +1 more source

Performance characterization of PON technologies [PDF]

open access: yesSPIE Proceedings, 2007
The simulation models for a typical PON layout are developed and three major PON technologies are considered. The models support the analysis of various important characteristic parameters, namely: 1) link budget for acceptable losses from splices, attenuation and splitters, 2) link performance characterization based on data (BER, SNR) or video ...
Alex Vukovic   +3 more
openaire   +1 more source

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