Results 101 to 110 of about 1,235,212 (309)
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Innovation Effects of Science-Related Technological Opportunities - Theoretical Considerations and Empirical Findings for Firms in the German Manufacturing Industry - [PDF]
This paper investigates the innovation effects of science-related technological opportunities. Against the background of theoretical considerations about the interrelation of innovation and the adaptation of external (knowledge) resources, the impacts of
Juergen Peters, Wolfgang Becker
core
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Synergistic effects of organizational innovation practices and firm performance [PDF]
Organizational innovation has been shown to be favourable for technological innovation. However, the question of which organizational practices should be combined ? and thus of their compatibility ? remains unanswered. We here empirically investigate the
MOTHE Caroline +2 more
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
How agricultural technological innovation influences carbon emissions: insights from China
Frontiers in Sustainable Food SystemsUnder the context of global warming, the continuous rise in greenhouse gas emissions has become a critical concern. As a significant source of greenhouse gas emissions, the carbon emissions from agriculture exert a considerable impact on climate change ...
Fengxia Tang +3 more
doaj +1 more source
Technological Opportunities, Absorptive Capacities, and Innovation [PDF]
The aim of this paper is to analyze the effects of technological opportunities on the innovation activities of firms, depending on their absorptive capacities.
Juergen Peters, Wolfgang Becker
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The importance of R&D subsidies and technological infrastructure for regional innovation performance - A conditional efficiency approach [PDF]
The importance of R&D subsidies for innovation activities is highlighted by numerous firm-level studies. These approaches miss however the systematic regional character of innovation activities and potential firm-spanning effects of this policy measure ...
Charlotte Schlump, Tom Broekel
core
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source