Results 111 to 120 of about 679,114 (307)

Designing transition paths for the diffusion of sustainable system innovations. A new potential role for design in transition management? [PDF]

open access: yes, 2008
Copyright @ 2008 Umberto AllemandiIt is a shared opinion that the transition towards sustainability will be a continuous and articulated learning process, which will require radical changes on multiple levels (social, cultural, institutional and ...
Ceschin, F, Kemp, R, Vezzoli, C
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Turkish Physical Education Teachers’ Use of Technology: Application and Diffusion of Technological Innovations

open access: yesEducation Sciences
The purpose of this study was to determine Turkish physical education (PE) teachers’ level of technological innovation use and attitudes regarding their applications and diffusion. This study consisted of 678 Turkish PE teachers. In total, 265 (39.1%) of
Ferman Konukman, Bijen Filiz
doaj   +1 more source

Technological Innovations in the Census of Agriculture [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2018
Unparalleled changes in technology such as remote sensing, mobile devices (e.g. tablets, smartphones), Web questionnaires, online dissemination of results (e.g.
Jairo Castano
doaj  

The impact of innovation on employment in Europe: An analysis using CIS data [PDF]

open access: yes
Technological progress in western economies has contributed to an immense rise in productivity, incomes and goods available over the last hundred years. Though not to the same extent as productivity and wages, population and employment have risen as well.
Blechinger, Doris   +3 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

ELABORATION AND IMPLEMENTATION OF ECOLOGICAL PRODUCT AND PROCEDURAL INNOVATIONS AS CONSTITUENTS OF TECHNOLOGICAL COMPETITIVENESS OF THE REGIONAL ECONOMY

open access: yesRussian Journal of Economics and Law, 2011
The work specifies the apparatus criticus of elaboration of ecology-oriented technological innovations, presents the topical types and techniques of assessment of product and procedural ecology-oriented innovations, improves the model of forming product ...
E. Shaimiyeva
doaj  

How to explore new business models for technological innovations [PDF]

open access: yes
Technological innovation projects must be accompanied by upstream strategic analysis on the related value creation model. It can be shown that generally successful technological innovations have also involved business model innovation. Exploration of new
Marie-Laurence Caron-Fasan   +1 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The complete mitochondrial genome of Tephrinectes sinensis and its phylogenetic position relative to Paralichthyidae

open access: yesMitochondrial DNA. Part B. Resources
Tephrinectes sinensis, an endemic flatfish from China’s coastal waters, has remained taxonomically contentious owing to its distinctive morphology and osteology.
Wu-Wei Chen   +7 more
doaj   +1 more source

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