Results 31 to 40 of about 3,019,476 (237)
DEVELOPMENT OF MODELS OF TECHNOLOGY TRANSFER FOR PUBLIC WORKS
The aim of the study is to improve the efficiency of technology transfer management in public works by developing a model for the reasonable definition of transfer objects and their components. The subject of the study are models of reasonable definition
Yuriy Kharytonov +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Effectiveness analysis of the kulback’s information measure in the technological objects monitoring
The technological objects’ state monitoring is focused on the following purposes: to ensure the production processes effective functioning and to improve the quality and competitiveness of the products.
Skatkov Alexander +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The article presents a systematic review of scientific articles devoted to applications of multi-criteria optimization methods, published in open sources in 2013-2023, conducted in accordance with the PRISMA recommendations. The main optimization methods
Maksim A. Zolotarev
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Schon immer waren Technologien zentral für die Produktion, Distribution und Rezeption von Medieninhalten. Die Medienforschung der vergangenen Jahre rückt diese materiale Ebene bzw. Materialität von Medienkommunikation wieder verstärkt in den Fokus. Diese
Nele Heise
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
ON KNOWLEDGE SYSTEM FORMATION IN INTELLIGENT ELECTRONIC DOCUMENTATION OF MECHATRONIC OBJECTS
The recommendations on building the knowledge system based on the conceptual approach to the mechatronic technological object documentation are made. The example of the intelligent management application for the improvement in the machine part cutting ...
Andrey K. Tugengold +2 more
doaj

