Results 131 to 140 of about 20,873,422 (384)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
The location of the Spanish technological centers [PDF]
The Technological Centers have been created with the aim of being a supplier of different R&D's activities and services for those entreprises with a lack of material and financial resources to develop by themselves an innovation process.
Fuster Olivares, Antonio +2 more
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Determination of required measurement accuracy of parameters of technological process on Volnogorsk mining and smelting complex [PDF]
, 2013 На основании определения дисперсий технологических показателей в обогатительной технологии с помощью преобразования спектров дисперсий исходного потока полезного ископаемого определены требования к точности измерительного устройства этих показателей.На ...
Lysenko, А.А. +4 more
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YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Technological Capabilities of a Special Strategy for Processing Cycloidal Helical Surfaces with a Non-Profiled Tool [PDF]
, 2021 А. А. Гончаров, A.S. Vasiliev
openalex +1 more source
Process Technology of Biotechniques*
, 1992 Publisher Summary This chapter discusses process technology of biotechniques. The number of applications of biological treatment systems for off-gas purification has strongly increased. The application of a biological treatment system is based upon the microbial degradability of the compounds present in the waste gas.
Diks, R.M.M., Ottengraf, S.P.P.
openaire +3 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
SELECTIVE BREEDING, HERITABLE CHARACTERISTICS AND GENETIC-BASED TECHNOLOGICAL CHANGE IN THE CANADIAN BEEF CATTLE INDUSTRY [PDF]
The paper presents an examination of genetic-based technological change in the Canadian beef cattle industry. A model of technological change is explicitly developed in characteristics space. Production functions with genetic characteristics as arguments
Kerr, William A.
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source