Results 171 to 180 of about 399,661 (313)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Managing technological sovereignty: a systematic review of semiconductor industry policy and regional ecosystem governance. [PDF]

Front Res Metr Anal
Cai J, Fang X, Yin Y, Yu Y, Wang C, Ho WI, Hu H.   +6 more
europepmc   +1 more source

ISO 19157 standard application in technological process of the production of digital topographic maps [PDF]

, 2014
Siniša Drobnjak, Stevan Radojčić, Branko Božić   +2 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

How metaverse-enabled digital transformation drives sustainable supply chain innovation: evidence from Pakistan's textile industry. [PDF]

Sci Rep
Abdullah M, Ullah A, Jamal MF, Aldakheel EA, Khafaga DS, Ashraf S, Rasool Z.   +6 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Rapid adoption of bow technology across western North America ∼1,400 years ago. [PDF]

PNAS Nexus
Buchanan B, Hamilton MJ, Eren MI, Walker RS.   +3 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

From setting to vetting: using artificial intelligence for Single Best Answer questions review. [PDF]

Korean J Med Educ
Ng O, Han SP, Lee MHM, Phua DH.
europepmc   +1 more source

A Model of Virtual Training Application for Simulation of Technological Processes

, 2015
Bakhyt Mukhanov, Zhanar Omirbekova, Madina Alimanova, Shynara Jumadilova, Dinara Kozhamzharova, Olimzhon Baimuratov   +5 more
openalex   +1 more source