Results 221 to 230 of about 2,651,920 (362)

PCV103 TECHNOLOGICAL INNOVATION AND THE DECISION-MAKING PROCESS IN ITALIAN HOSPITALS

, 2008
S Bartoli, Rosanna Tarricone, S Benussi, Pierluigi Stefàno, Guido Marinelli   +4 more
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Optimizing The Technological Process Of Ro-La Transport

, 2008
T. J. Mlinaric, T. Plesa, D. Baric
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Evolution and Challenge of “Monozukuri”―Invention of Cutting Edge Materials and Innovation by Technological Fusion of Marterials and Processing

, 2008
Chiaki Tanaka
openalex   +2 more sources

NEV battery recycling innovation strategy considering pro-social behavior from the game theory perspective. [PDF]

Sci Rep
Xu Y, Zheng Y, Xu N.
europepmc   +1 more source

TECHNOLOGICAL PROCESS OF SOUND-ABSORBING PANELS [PDF]

Annals of the Oradea University: Fascicle Management and Technological Engineering, 2010
A. UNGUR Patricia, Mariana ARGHIR, Ioan MIHAILA, A. POP Petru, Florin MARCU   +4 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Investigation of antibacterial activity of supercritical extracts of plants, as well as of extracts obtained by other technological processes on some bacteria isolated from animals

, 2009
Dušan Mišić, Ašanin Ružica, Jasna Ivanović, Irena Žižović   +3 more
openalex   +2 more sources

Evaluation of scientific and technological innovation efficiency at Shandong Vocational and Technical University of international studies: A two-stage DEA model approach. [PDF]

PLoS One
Zeng J, Sun T, Zhang L.
europepmc   +1 more source