Results 251 to 260 of about 2,386,746 (336)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Retraction: Economic expansion and innovation: A comprehensive analysis of Pakistan's path to technological excellence. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Safety evaluation of the food enzyme α-amylase from the non-genetically modified <i>Bacillus licheniformis</i> strain TTME 6280 KY. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Fernández-Fraguas C, Cavanna D, Lunardi S, Liu Y.   +16 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Innovative lipid delivery systems in ruminant diets: the role of spray drying. [PDF]

Front Vet Sci
de Oliveira TTB, Ferreira TCS, Tavares PPLG, Correia PRC, Ribeiro CVDM, de Souza CO.   +5 more
europepmc   +1 more source

THE INSTITUTIONALIZATION PROCESS OF LAW N. 10.639/03 IN THE NETWORK FEDERAL THE EDUCATION PROFESSIONAL, SCIENTIFIC AND TECHNOLOGICAL: AN ANALYSIS FROM THE INSTITUTIONAL PROJECTS OF THE FEDERAL INSTITUTES AND THE FEDERAL CENTERS OF TECHNOLOGICAL EDUCATION

, 2019
Marcus Vinícius Fonseca, Laura Fernanda Rodrigues da Rocha   +1 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Investigation of the Possibilities for Infrared Diagnosis of Peirce-Smith Converters in Non-Ferrous Metallurgy. [PDF]

Materials (Basel)
Mihailov E, Choshnova D, Ivanova M, Asenova M.   +3 more
europepmc   +1 more source

[The technological process].

La Medicina del lavoro, 1983
V, Amicarelli, M, Dompè
openaire   +1 more source