Results 41 to 50 of about 25,909 (264)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

دور الاقتصاد الرقمي في تحقيق النمو الاقتصادي (دراسة تحليلية). [PDF]

مجلة البحوث القانونية و الاقتصادية
يشهد العالم في ظل الثورة التكنولوجية الرابعة تحولًا عميقًا في بنية الاقتصاد وأساليب إدارته، حيث برز الاقتصاد الرقمي بوصفه قوة دافعة لإعادة تشكيل الأنشطة الاقتصادية وتعزيز كفاءتها، بما يسهم في دعم مسارات النمو الاقتصادي وتحقيق التنمية المستدامة. وقد اتجهت
محمد صدام محمد
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

The Organizational Culture and Innovation of Enterprises in the Era of the Fourth Industrial Revolution

Studies in Logic, Grammar and Rhetoric
The fourth industrial revolution, characterized by the development of advanced technologies such as artificial intelligence, the Internet of Things and automation, is radically changing the context of functioning of modern enterprises.
Protasiewicz Anna, Zalesko Elzbieta
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

From the Theory of the African Origin of Humankind to Modern Social, Legal and Technological Innovations: a Brief Analytical Excursion into Anthroposociogenesis

Journal of Digital Technologies and Law
Objective: to trace the evolution of humanity and to identify the role of various social institutions in order to understand the existential role of laws aimed at ensuring the coexistence of society in the context of technological innovations.Methods ...
D. Traore
doaj   +1 more source

The inherent purpose of ontology in ecology: The immutable use of Hans Jonas’s works [PDF]

Meta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2014
Theresa Morris, Hans Jonas’s Ethic of Responsibility: From Ontology to Ecology, Albany, NY: State University of New York Press, SUNY Series in Environmental Philosophy and Ethics, 2013, 236 p.
Raluca Deleanu
doaj  

The Revolution of Capitalist Relations Induced by the Technological Revolution of Electronics

World Review of Political Economy, 2018
Capitalism is in a dialectical leap to socialism, the next human stage. The laws of dialectical materialism and of historical materialism are examined. The scientific and technical revolution is examined.
Bruce E. Parry
doaj   +1 more source