Results 191 to 200 of about 73,152 (264)

Education 5.0: Technological transformations and health perspectives for sustainable development. [PDF]

J Educ Health Promot
Nikum K, Singh P, Pachori S, Bani K.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Evolution of China's industry-university-research-hospital collaboration in AI medical devices and implications for medical institutions and public health governance. [PDF]

Front Public Health
Hu F, Yang H, Ren Z, Wang X, Zhou H, Yang S, Wei S, Hu J, Zhao S, Hu H, Cheng J.   +10 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Integrating AI in seed science: Toward an intelligent design paradigm. [PDF]

Plant Commun
Zhang Y, Du J, Huang G, Zhao Y, Man P, Song A, Zhao Y, Men Q, Wang C, Guo M, Guo X, Zhao C.   +11 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Curcumin in Food Technology: Trends, Challenges, and Innovative Perspectives Through Bibliometrics. [PDF]

Food Sci Nutr
Bueno VD, Souto AA.
europepmc   +1 more source

Achieving bottom-up ethical, legal, and societal implications and responsible research and innovation in the synthetic biology research community from the Japanese context. [PDF]

Front Genet
Matsuo M, Hagino K, Kawata S, Hasunuma T, Honda K.   +4 more
europepmc   +1 more source

Knowledge embedded wind tunnel typical pressure vessel design optimization method research. [PDF]

PLoS One
Yang Y, Yan S, Xie Q, Liu B, Yan X, Yang Z, Ding H.   +6 more
europepmc   +1 more source

Transforming the automotive industry: Defining, clustering, and efficiency analysis of the next-generation automotive ecosystem. [PDF]

PLoS One
Shon M, Kim J, Kim H.
europepmc   +1 more source