Results 221 to 230 of about 653,731 (310)

Developing Scenario-Based Strategies for Health, Climate, and Environmental Preparedness: The One Health, One Earth Approach. [PDF]

Geohealth
Abadi AM, Brumfield KD, Usmani M, Jiang G, Chakraborty TC, Wang Y, Zhou Z, He C, Qiu M, Stowell JD, Fritz D, Kumar S, Guo Q, Xiong Y, Destouni G, Xiao Q, Hu XC, Fong KC, Hang Y, Nielsen-Gammon J, Habre R, Bratburd JR, Tessum CW, Jutla A, Colwell RR, Filippelli GM, Nguyen TH.   +26 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Plastamination, Human Health, and Countries' Cultural Orientation: An Exploratory Study on Prevention Strategies and Organizational Policies and Practices. [PDF]

Int J Environ Res Public Health
Perna G, Meccariello R, Varriale L.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Reducing Interface Energy Loss of Perovskite Solar Cells by Molecular Engineering of Hole-Transporting Materials. [PDF]

Angew Chem Int Ed Engl
Shao G, Yang SG, Chen J, Wang D, Zhang JJ, Zhou ZK, Xiao J, Jiang L, Wu ZZ, Kanda H, Yang H, Qiu Z, Hu R, Li X, Khan AA, Zhang Y, Xia J, Nazeeruddin MK.   +17 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Editorial: Enhancing public health workforce competencies: AI integration and post-pandemic educational reforms. [PDF]

Front Public Health
Su Z, Jiang J, Nie JB, Gray KM, McDonnell D, da Veiga CP, Xiang YT.   +6 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Artificial intelligence, robotics, and person-centered care in nursing and midwifery education: qualitative study to develop an augmented caring pedagogy model. [PDF]

BMC Med Educ
Sengul T, Uncu B, Sarıköse S, Kaya N, Lopez V, Kirkland-Kyhn H.   +5 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source