Brazil at the Forefront: What Does It Take To Be Net-Zero by 2040. [PDF]
Angelkorte G +15 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Research on the decision-making of high-tech manufacturing enterprises for energy conservation and emission reduction driven by industrial green microgrids under the green credit regulatory system. [PDF]
Qin H +5 more
europepmc +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Stakeholder Perspectives on Facilitators of and Barriers to the Implementation of Internet of Things-Equipped Powered Wheelchairs in Sweden: Qualitative Case Study. [PDF]
Borg J, Elf M, Brantnell A, Palm K.
europepmc +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Computer-Aided Detection Systems: Can Efficacy Be Evaluated as a Single Technological Concept? [PDF]
Kamba S, Sumiyama K.
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Identification of key elements and driving mechanisms in university early warning systems for suicide and violence crises-Based on the TOE framework and the DEMATEL-ISM model. [PDF]
Wang H.
europepmc +1 more source

