Results 41 to 50 of about 2,624,914 (308)

Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

npj Systems Biology and Applications
Combination therapy is well established as a key intervention strategy for cancer treatment, with the potential to overcome monotherapy resistance and deliver a more durable efficacy.
Orsolya Papp, Viktória Jordán, Szabolcs Hetey, Róbert Balázs, Valér Kaszás, Árpád Bartha, Nóra N. Ordasi, Sebestyén Kamp, Bálint Farkas, Jerome Mettetal, Jonathan R. Dry, Duncan Young, Ben Sidders, Krishna C. Bulusu, Daniel V. Veres   +14 more
doaj   +1 more source

Glaucoma Identification Using Convolutional Neural Networks Ensemble for Optic Disc and Cup Segmentation

IEEE Access
Glaucoma is one of the diseases that can cause incurable blindness. The first noticeable symptoms appear only when the disease has progressed but an early diagnosis of the disease prevents the severe consequences of disease progression. In this paper, we
Sandra Virbukaite, Jolita Bernataviciene, Daiva Imbrasiene   +2 more
doaj   +1 more source

Short-Term Forecasting of Dockless Bike-Sharing Demand with the Built Environment and Weather

Journal of Advanced Transportation, 2023
To help related operators to allocate and dispatch the number of bike-sharing and provide good guidance for setting up electronic fences, this paper proposes a spatiotemporal graph convolution network prediction model (SGCNPM) with multiple factors to ...
Yang Yang, Xin Shao, Yuting Zhu, Enjian Yao, Dongmei Liu, Feng Zhao   +5 more
doaj   +1 more source

Series with Binomial-like Coefficients for the Investigation of Fractal Structures Associated with the Riemann Zeta Function

Fractal and Fractional, 2022
The paper continues the study of efficient algorithms for the computation of zeta functions over the complex plane. We aim to apply the modifications of algorithms to the investigation of underlying fractal structures associated with the Riemann zeta ...
Igoris Belovas, Martynas Sabaliauskas, Lukas Kuzma   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

School leadership and educational effectiveness: Lithuanian case in comparative perspective

Management : Journal of Contemporary Management Issues, 2019
This paper examines the links between student learning and school leadership focusing on Lithuania in comparative perspective. Different aspects of school leadership areas are being outlined, but after a more thorough analysis of the educational ...
Rimantas Želvys, Rita Dukynaitė, Jogaila Vaitekaitis, Audronė Jakaitienė   +3 more
doaj   +1 more source

Big Data technologies: A survey

Journal of King Saud University - Computer and Information Sciences, 2018
Developing Big Data applications has become increasingly important in the last few years. In fact, several organizations from different sectors depend increasingly on knowledge extracted from huge volumes of data. However, in Big Data context, traditional data techniques and platforms are less efficient.
Ahmed Oussous, Fatima-Zahra Benjelloun, Ayoub Ait Lahcen, Samir Belfkih   +3 more
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis of Education Systems Performance in European Countries by Means of PCA-DEA

Informatics in Education, 2018
Many countries have focused on the improvement of education system performance. Small number of studies consider system of a country as unit of assessment where indicators represent all levels of education system. In the paper, we propose the methodology
Audrone JAKAITIENE, Antanas ZILINSKAS, Dovile STUMBRIENE   +2 more
doaj   +1 more source

Parking Resource Allocation Optimization Framework Based on a Two-Level Grid Model

Journal of Advanced Transportation, 2022
With the rapid increase in vehicle population, solving difficult-to-park and inconvenient-to-park problems has become a necessity for sustainable transportation in major cities. This study investigated the parking resource allocation optimization problem
Haonan Guo, Yun Wang, Xuedong Yan, Yunlin Guan, Yu Zhou   +4 more
doaj   +1 more source