Results 11 to 20 of about 90,903 (193)
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
DETDet: Dual Ensemble Teeth Detection [PDF]
arXiv, 2023 The field of dentistry is in the era of digital transformation. Particularly, artificial intelligence is anticipated to play a significant role in digital dentistry. AI holds the potential to significantly assist dental practitioners and elevate diagnostic accuracy.
arxiv
Journal of Applied Clinical Medical Physics, EarlyView.Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye +16 more
wiley +1 more source
X-ray Imaging Using a Hybrid Photon Counting GaAs Pixel Detector [PDF]
Nucl.Phys.Proc.Suppl.78:491-496,1999, 1998 The performance of hybrid GaAs pixel detectors as X-ray imaging sensors were investigated at room temperature. These hybrids consist of 300 mu-m thick GaAs pixel detectors, flip-chip bonded to a CMOS Single Photon Counting Chip (PCC). This chip consists of a matrix of 64 x 64 identical square pixels (170 mu-m x 170 mu-m) and covers a total area of 1.2 ...
arxiv +1 more source
Advanced Engineering Materials, EarlyView.A metallic implant's higher stiffness compared to the surrounding bone leads to stress shielding problems, causing bone density reduction and bone growth interference in pediatric patients. 3D‐printed triply periodic minimal surface structures present a promising engineering solution.
Ali Ebrahimzadeh Dehaghani +4 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Additive manufacturing of magnesium alloys by laser is difficult because the melting point of the oxide layer is much higher than the evaporation temperature of the metal underneath. Making the oxide layer thinner can solve this problem. Alloying magnesium with strontium makes the oxide layer thinner, especially at 0.5 wt%.
Elmar Jonas Breitbach +8 more
wiley +1 more source
Self-Supervised Learning with Masked Image Modeling for Teeth Numbering, Detection of Dental Restorations, and Instance Segmentation in Dental Panoramic Radiographs [PDF]
arXiv, 2022 The computer-assisted radiologic informative report is currently emerging in dental practice to facilitate dental care and reduce time consumption in manual panoramic radiographic interpretation. However, the amount of dental radiographs for training is very limited, particularly from the point of view of deep learning.
arxiv