Results 31 to 40 of about 24,241 (244)
Wejdan M Arif King Saud University, College of Applied Medical Sciences, Department of Radiological Sciences, Riyadh, Saudi ArabiaCorrespondence: Wejdan M Arif, Email warif@ksu.edu.saStudy Purpose: This study aims to analyze radiologic technology student’
Arif WM
doaj +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Background Tumor-associated macrophages (TAMs) frequently adopt an M2-like, immunosuppressive state that promotes tumor growth and therapy resistance. Reprogramming TAMs toward a pro-inflammatory M1 phenotype is a promising strategy to remodel the tumor ...
Nathupakorn Dechsupa +11 more
doaj +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
The aim of the current study was to synthesize polyvinyl alcohol Cuprous Oxide composite films (PVA/Cu2O) for radiation detection depending on optical changes.
Mohammed Ahmed Ali Omer +1 more
doaj +1 more source
Effects of obesity on the lipid and metabolite profiles of young adults by serum 1H-NMR spectroscopy [PDF]
Background Overweight (OW) is considered a risk for various metabolic diseases. However, its effects as a mechanism that alters the metabolite profiles remain unclear.
Duanghathai Pasanta +4 more
doaj +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Thanh Thao Nguyen, Ngoc Thanh Hoang, Thao Van Nguyen, Hien Thi Ha Department of Radiology, University of Medicine and Pharmacy, Hue University, Hue, VietnamCorrespondence: Thanh Thao Nguyen, Department of Radiology, University of Medicine and Pharmacy ...
Nguyen TT, Hoang NT, Nguyen TV, Ha HT
doaj
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source

