Results 91 to 100 of about 17,536,486 (283)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Capillary Agglutination Technology [PDF]

open access: yes, 2006
In medical diagnostic tests, including pregnancy testing and tests for typed red blood cells, a small fluid sample is placed at one end of a capillary channel, which has been lined with a dried reagent.
Breward, Chris, Richardson, Giles
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Europe's clean technology investment challenge [PDF]

open access: yes
Development and deployment of clean-energy technologies is crucial if climate targets are to be met cost-effectively. The European Union already has a plan that deals with these issues: the Strategic Energy Technology Plan, which has become central to ...
Reinhilde Veugelers
core   +1 more source

Xrdp Remote Desktop Solution Evaluation Report [PDF]

open access: yes, 2016
The Technology Investigation Service's Technology Evaluation team conducted an evaluation of the XRDP remote terminal tool.
The Technology Investigation Service's Technology Evaluation Team
core  

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