This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Retracted: Antimicrobial Analysis of Biosynthesized Lectin-Conjugated Gold Nanoparticles
Adsorption Science and Technology
doaj +1 more source
Longitudinal evidence of technology-enhanced, individualized neuromotor rehabilitation on autonomy, cognition, quality of life, and psychological well-being: Pilot multi-sample study. [PDF]
Zanatta F +8 more
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Retracted: Predicting Carbon Residual in Biomass Wastes Using Soft Computing Techniques
Adsorption Science and Technology
doaj +1 more source
Innovative adoption model for digital health technologies among elderly with chronic diseases: integrating Unified Theory of Acceptance and Use of Technology and Knowledge-Attitude-Practice model in a survey of 1222 patients in Shanghai. [PDF]
Chen Y +7 more
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Identifying the Demographic and Internet Use Characteristics of Technology-Facilitated Child Sex Offenders Operating in the Australian, U.S. and U.K. General Population. [PDF]
Salter M +5 more
europepmc +1 more source

