Results 81 to 90 of about 7,254,348 (387)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Teknoloji Bağımlılığının Semptomlar Temelinde İncelenmesi

Online Academic Journal of Information Technology, 2018
Teknoloji bağımlılığı üzerine kesin bir uzlaşı olmamasına rağmen yapılan çalışmalarda başlangıçta belirli bir amaç için kullanılan teknolojilerin git gide hayatın kendisi olmaya başladığı vurgulanmaktadır.
Özhan Tıngöy, Mert Küçükvardar
doaj   +1 more source

Old Games, Same Concerns: Examining First Generation Video Games Through Popular Press Coverage from 1972-1985 [PDF]

, 2013
This study explores early video game technology by examining video game fears in the popular press in the 1970s and 1980s. This textual analysis examines games during their formative years, assesses risks associated with new technology, and encourages ...
Rogers, Ryan
core   +1 more source

Media use during adolescence: the recommendations of the Italian Pediatric Society. [PDF]

, 2019
BACKGROUND: The use of media device, such as smartphone and tablet, is currently increasing, especially among the youngest. Adolescents spend more and more time with their smartphones consulting social media, mainly Facebook, Instagram and Twitter ...
Agostiniani R, Banderali G, Bozzola E, Bozzola M, Caruso C, Chiara A, Corsello G, Del Vecchio A, Memo L, Peroni D, Ruggiero M, Spina G, Staiano AM, Turra R, Vecchio D, Villani A   +15 more
core   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Relationship between video game addiction and bladder/bowel dysfunction in children

Biomédica: revista del Instituto Nacional de Salud
Introduction. Video games have a strong influence on children and adolescents. Video game addiction has negative effects on children’s health. Objective. To determine the relationship between video game addiction and bladder/bowel dysfunction in children.
Öznur Tiryaki, Dilek Menekşe, Nursan Çınar   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The Social Media and Technology Addiction and Its Associated Factors among University Students in Lebanon Using the Media and Technology Usage and Attitudes Scale (MTUAS)

Journal of Computer and Communications, 2019
The contemporary developments of Information and Communication Technologies usage have fueled a popular concern. The young people are experiencing technology addiction behavior due to excessive media and technology usage.
Hala Sabbah, R. ecirc, ve Berbari, Rania Khamis, Dalia Zorkot, Sanaa Sabbah, N. Droubi, Ibtissam Sabbah   +7 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Internet gambling: an overview of psychosocial impacts [PDF]

, 2005
Technological innovation has always played a role in the development of gambling behaviour, primarily through providing new market opportunities. Early prevalence studies of Intemet gambling in the UK, Canada and the US have shown that Intemet gambling ...
Griffiths, Mark, Parke, Adrian, Parke, Jonathan, Wood, Richard   +3 more
core