Results 91 to 100 of about 1,536,208 (306)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Role of Production Risk in Sustainable Land-Management Technology Adoption in the Ethiopian Highlands [PDF]

This paper provides empirical evidence of production risk impact on sustainable land- management technology adoption, using two years of cross-sectional plot-level data collected in the Ethiopian highlands.
Kassie, Menale, Köhlin, Gunnar, Yesuf, Mahmud   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Technology Adoption and Product Differentiation: Market-Level Effects [PDF]

The focus of the microeconomic technology adoption literature has been on the adoption and diffusion of new innovations: who adopts, and when they adopt.
An, Henry
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Bibliometric Analysis of Research on Financial Technology (FinTech) in the ASEAN Region: Research Streams, Influential Works, and Future Research Paths

Jurnal Siasat Bisnis
Purpose – This paper aims to identify trends and research mapping of financial technology (FinTech) in the ASEAN Region that have been of interest to academics and practitioners through the help of Vosviewers' application in visualizing the data.  
Nurul Wahdaniyah, Achmad Nurmandi, Muhammad Younus   +2 more
doaj   +1 more source

Exploring the Internet of Things adoption in the Fourth Industrial Revolution: a comprehensive scientometric analysis [PDF]

Journal of Innovative Digital Transformation
Purpose – This study examines the adoption of the Internet of Things (IoT) within the Fourth Industrial Revolution (4IR) context, using a comprehensive scientometric analysis to map the evolution of IoT adoption.
Diana Teresa Parra-Sánchez
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Recent Developments in Individual Difference Research to Inform the Adoption of AI Technology

Systems
Artificial intelligence (AI) technology has become one of the most frequently discussed subjects in the development of technology in recent years. Due to its incredible pattern recognition, it can help humans complete work much faster than before with ...
Luke Symasek, Taylor Yeazitzis, Kristin Weger, Bryan Mesmer   +3 more
doaj   +1 more source

Determinants of technology adoption in Mexico [PDF]

The author tries to identify the impact of firm-, region-, and industry-specific characteristics on technology adoption by Mexican firms. Cross-sectional and panel data from 1992-99 show that the firms most likely to adopt new technology are large, train
Lopez-Acevedo, Gladys
core