Results 121 to 130 of about 9,214,492 (308)
Recent Developments in Individual Difference Research to Inform the Adoption of AI Technology
SystemsArtificial intelligence (AI) technology has become one of the most frequently discussed subjects in the development of technology in recent years. Due to its incredible pattern recognition, it can help humans complete work much faster than before with ...
Luke Symasek +3 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Simon Keogh: stories about the adoption experience in Australia
, 2010 This story is part of the History of Adoption, a four-year national research project funded by the Australian Research Council, 2009 ...
Keogh, Simon
core
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Marian Jacobs: stories about the adoption experience in Australia
, 2010 This story is part of the History of Adoption, a four year national research project funded by the Australian Research Council, 2009 ...
Jacobs, Marian
core
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Report of the Adoption Board 1988
, 1988 The number of applications for adoption orders made to the Board in 1988 reflects the continuing decline in the number of children being placed for adoption. Last year the Board received 714 applications for adoption orders.
Adoption Authority of Ireland
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Robin Rose: stories about the adoption experience in Australia
, 2010 This story is part of the History of Adoption, a four year national research project funded by the Australian Research Council, 2009 ...
Rose, Robin Cecil
core
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source