Results 41 to 50 of about 254,499 (313)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Jurnal Penelitian Sosial dan Ekonomi Kehutanan, 2014 Low rate adoption of soil and water conservation technologies, such as agroforestry systems and terrace farming, is still prevalent in a number of areas proned to water erosion.
Nana Haryanti
doaj +1 more source
Measure of Clinical Information Technology Adoption [PDF]
Healthcare Informatics Research, 2013 ObjectivesThe objective of this study was to create a new measure for clinical information technology (IT) adoption as a proxy variable of clinical IT use.MethodsHealthcare Information and Management Systems Society (HIMSS) data for 2004 were used.
Jinhyung Lee, Young-Taek Park
doaj +1 more source
Co-adoption pathways toward a low-carbon energy system
iScience, 2023 Summary: Low-carbon technology adoption is an essential element of energy transitions toward net-zero emissions around the world. To exploit the full potential of low-carbon technologies, households should ideally co-adopt multiple low-carbon ...
Maria Lagomarsino +4 more
doaj +1 more source
The technology-behavioral compensation effect: Unintended consequences of health technology adoption [PDF]
, 2023 Tobias Wolf +3 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Understanding the Determinants of RFID Adoption in Iran Case study: Automotive Manufacturing Industry [PDF]
چشمانداز مدیریت صنعتی, 2013 The radio identification technology (RFID) may change the nature of many industries in future years. The study concentrates on the factors affecting the adoption of RFID technology in the automotive parts manufacturing industry in Iran. The RFID adoption
Aliakbar Jowkar, Ali nasirzonouzi
doaj
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source