Results 51 to 60 of about 254,499 (313)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An overview of the status, productivity and determinants of improved forage technology adoption in Ethiopia: a review

CABI Agriculture and Bioscience, 2023
In Ethiopia, the adoption of improved forage technology is low despite the fact that improved technology adoption can play a pivotal role in boosting livestock production and productivity in general and the dairy sub-sector in particular, thereby ...
Mamaru Tesfaye, Lemma Tessema
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Assessing personal disposition of individuals towards technology adoption

Future Business Journal, 2016
The present study has attempted to explore personal disposition of individuals towards technology adoption through the development of an index named as Technology Adoption Index.
Irbha Magotra, Jyoti Sharma, Supran Kumar Sharma   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Following Successfully: Followership and Technology Adoption

Prometheus, 2002
Most firms in most countries find themselves taking up new technology in the wake of pioneers or first-movers. A central question is how (and whether) such firms can make a success of being followers--in the time-related sense of adopting subsequently ...
Peter Hall, Iain L. Densten
doaj   +1 more source

Technology Adoption and Extension Strategies in Mediterranean Agriculture: The Case of Family Farms in Chile

Agronomy, 2020
Extension services play a crucial role by improving skills and access to information that result in greater farm level innovations, especially on family farms which are the predominant form of agriculture in the world.
Roberto Jara-Rojas, Romina Canales, José M. Gil, Alejandra Engler, Boris Bravo-Ureta, Carlos Bopp   +5 more
doaj   +1 more source

Income Inequality and Technological Adoption [PDF]

Journal of Economic Issues, 2017
We relate technological adoption (of different technologies) with income inequality. In the process, we discover that some technologies, such as aviation, cell phones, electric production, internet...
Santos, M., Sequeira, T. N., Ferreira-Lopes, A.   +2 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source