Results 61 to 70 of about 254,499 (313)

Exploring teachers’ technology adoption: linking TPACK knowledge and UTAUT-3 constructs

Discover Education
For a number of years now, the use of information and communication technology (ICT) in the education sector has grown significantly. The purpose of this study was to evaluate the relationships between teachers' perceived usage of technology and the ...
Rodnie Kgalemelo Mafa, Desmond Wesley Govender   +1 more
doaj   +1 more source

Simultaneity of Technology Adoption and Productivity

Journal of Agricultural and Resource Economics, 1994
A simultaneous equation generalized probit model is estimated to determine factors affecting technology adoption by California dairy farmers. Since productivity and technology choice are jointly determined, a single-equation approach to determine whether
Lydia Zepeda
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Facilitating the adoption of high‐throughput sequencing technologies as a plant pest diagnostic test in laboratories: A step‐by‐step description [PDF]

, 2022
B. S. M. Lebas, Ian P. Adams, Maher Al Rwahnih, Steve Baeyen, Guillaume J. Bilodeau, Arnaud G. Blouin, Neil Boonham, Thierry Candresse, Anne Chandelier, Kris De Jonghe, Adrian Fox, Yahya Z. A. Gaafar, Pascal Gentit, Annelies Haegeman, Wellcome Ho, Oscar P. Hurtado‐Gonzales, Wilfried Jonkers, Jan Kreuze, Denis Kutjnak, Blanca B. Landa, Mingxin Liu, François Maclot, Martha Malapi‐Wight, Hans J. Maree, Francesco Martoni, Natasha Mehle, A. Minafra, Dimitre Mollov, Adriana Gonçalves Moreira, Mark K. Nakhla, Françoise Petter, Alexander M. Piper, Julien Ponchart, Robbie Rae, Benoît Remenant, Yazmín Rivera, Brendan Rodoni, J. W. Roenhorst, Johan Rollin, Pasquale Saldarelli, Johanna Santala, Rose Souza‐Richards, D. Spadaro, David J. Studholme, Stefanie Sultmanis, R.A.A. van der Vlugt, Lucie Tamisier, Charlotte Trontin, Inés Vázquez-Iglesias, Cláudia S. L. Vicente, Bart van de Vossenberg, Thierry Wetzel, Heiko Ziebell, Sébastien Massart   +53 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The adoption of social media tools for enhancing small and medium enterprises' performance: A synthesis of innovation of diffusion and technology-organisation-environment frameworks [PDF]

, 2023
Leo T. Mataruka, Joe Muzurura
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Sequential Adoption and Cost Savings from Precision Agriculture

Journal of Agricultural and Resource Economics, 2016
Precision agricultural (PA) technologies can decrease input costs by providing farmers with more detailed information and application control, but adoption has been sluggish, especially for variable-rate technologies (VRT).
David Schimmelpfennig, Robert Ebel
doaj   +1 more source