Results 81 to 90 of about 2,767,655 (310)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Redesigning the internal spaces of the Saudi housing is an educational necessity for the role of the family in achieving Vision 2030

Journal of Architecture, Art & Humanistic Science
Education is one of the means of building and developing peoples, and one of the causes of progress and advancement...and the first thing that God revealed to His Profet, And university education in its stages Various of the highest levels of learning ...
Assist. Prof. Dr. Doaa Abdel Salam Hassan M. Salem Associate Professor Faculty of Engineering and Information Technology - Onaizah Private Colleges – KSA
doaj   +1 more source

Editorial: Methodological considerations in sports science, technology and engineering. [PDF]

Front Sports Act Living, 2023
Godfrey A, Stuart S, Kenny IC, Comyns TM.   +3 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Technology and engineering test of filling goaf with coal gangue slurry. [PDF]

Sci Rep, 2023
Xie S, Pan H, Gu W, Zhu L, Yue D, Chen D, Song T, Jiang Z.   +7 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Simulation on model predictive control for PMSM drive system based on double extended state observer

Journal of Measurement Science and Instrumentation, 2018
A novel double extended state observer（DESO）based on model predictive torque control（MPTC）strategy is developed for three-phase permanent magnet synchronous motor（PMSM）drive system without current sensor.In general,to achieve high-precision control,two ...
CUI Hong-wei, TENG Qing-fang, ZHU Jian-guo, GUO You-guang, Department of Automation & Electrical Engineering, Lanzhou Jiaotong University, Key Laboratory of Opto-technology and Intelligent Control   +6 more
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Engineering Vanderbilt; Vol. 51, No. 02, 2010

, 2010
Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of Engineering.* 2 * from the dean * 6 * cover story - The Infinite to the Finite: Vanderbilt Researchers Imagine the Future of Imaging Science and ...
Vanderbilt University. School of Engineering
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source