Results 151 to 160 of about 2,767,655 (310)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 1979 Thesis (Nucl.E.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1979.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Includes bibliographical references.by Kord S.
Smith, Kord Sterling
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System engineering applied to early phase offshore oil and gas projects
, 2020 Thesis: S.M. in Engineering and Management, Massachusetts Institute of Technology, System Design and Management Program, September, 2020Cataloged from the official version of thesis.Includes bibliographical references (pages 73-75).Companies around the ...
Johnson, Allison, S.M. Massachusetts Institute of Technology.
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The effects of geometrical changes on airflow of developing-world solar fruit dryers
, 2020 Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, May, 2020Cataloged from the official PDF of thesis.Includes bibliographical references (pages 43-45).Small fruit-drying operations are becoming increasingly ...
Tang, Lisa(Researcher in mechanical engineering)Massachusetts Institute of Technology.
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
World Journal of Engineering and Technology
World Journal of Engineering and Technology (WJET) is an open access journal published quarterly. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various issues and ...
Cristina Gentilini
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Blockchain technology in supply chain and logistics
, 2018 Thesis: S.M. in Engineering and Management, Massachusetts Institute of Technology, System Design and Management Program, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (pages 92-99).Blockchain technology is a peer-to-peer ...
Agarwal, Shweta, S.M. Massachusetts Institute of Technology
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A Method for Head-shoulder Segmentation and Human Facial Feature Positioning
Tongxin xuebao, 1998 Hu Tianjian Cai Dejun Department of Electrical and Information Engineering (Huazhong University of Science and Technology +1 more
doaj +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source