Results 131 to 140 of about 2,140,826 (257)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

An economic and engineering assessment of plasma-sprayed ceramic coatings

open access: yes, 1988
Thesis: M.S., Massachusetts Institute of Technology, Department of Mechanical Engineering, 1988Bibliography: leaves 86-87.by Olivier de Botton.M.S.M.S.
Botton, Olivier de.
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

TECHNOLOGY OF OPEN-ENDED ENGINEERING IN TRAINING OF ENGINEERS

open access: yesВысшее образование в России, 2017
The article presents the authors’ technology of interdisciplinary open-ended engineering. This technology is an integrated teaching method that significantly increases the practical component in the educational program.
A. P. ISAEV   +2 more
doaj  

A flexible integrated computer system for engineering geology education

open access: yes, 1989
Thesis: M.S., Massachusetts Institute of Technology, Department of Civil Engineering, 1989Includes bibliographical references (leaf 56).by Matthew Grebner.M.S.M.S.
Grebner, Matthew.
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Engineering properties of the Orinoco Clay

open access: yes, 1981
Thesis (Civ.E)--Massachusetts Institute of Technology, Dept. of Civil Engineering, 1981MICROFICHE COPY AVAILABLE IN ARCHIVES AND ENGINEERING.Bibliography: leaves 107-108.by Robert William Day.Civ.
Day, Robert William
core  

Designing a project curriculum to introduce girls to mechanical engineering [PDF]

open access: yes, 2006
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.Includes bibliographical references (p. 16).The Women's Technology Program was created in MIT's Electrical Engineering and Computer Science department to expose ...
Yang, Sandie (Sandie S.)
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy