Results 91 to 100 of about 2,140,826 (257)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Pengembangan Modul Matematika dengan Pendekatan Science, Technology, Engineering, And Mathematics (STEM) pada Materi Segiempat

open access: yesDesimal, 2018
This study aims to determine the feasibility of mathematical modules with STEM approach and the response of learners and teachers to the attractiveness of the module.
Taza Nur Utami   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Machinery monitoring technology design methodology for determining the information and sensors required for reduced manning of ships

open access: yes, 2000
Thesis (Nav.E.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering; and, (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2000.Includes bibliographical references (p. 115-116).by Brian P.
Murphy, Brian P. (Brian Patrick), 1963-
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Aircraft Interior Design And Satisfaction For Different Activities; A New Approach Toward Understanding Passenger Experience

open access: yesInternational Journal of Aviation, Aeronautics, and Aerospace, 2019
Among airlines and aircraft manufacturers there is much attention for passenger experience. However, there is not much literature on how the activities of passengers can be supported by the aircraft interior. The current study focuses on the need finding
Golnoosh Torkashvand   +2 more
doaj   +1 more source

Commercialization of QD WLED technology

open access: yes, 2006
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2006.Includes bibliographical references.It is well known that the use of high-brightness LEDs for illumination has the potential to substitute ...
Zhao, Xinyue, M. Eng. Massachusetts Institute of Technology
core  

Remanufacturing technology [PDF]

open access: yes, 1983
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1983.MICROFICHE COPY AVAILABLE IN ARCHIVES AND ENGINEERING.Vita.Includes bibliographical references.by Tomás Agustin González Laugier.M ...
Gonzalez, Tomas A
core  

Towards engineering living functional materials

open access: yes, 2021
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, February, 2021Cataloged from the official PDF version of thesis.Includes bibliographical references (pages 206-221).Synthetic biology has become one of the most ...
Tang, Tzu-Chieh,Ph. D.Massachusetts Institute of Technology.
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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