Results 71 to 80 of about 1,915,193 (258)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Editorial: Highlights in sports science, technology and engineering 2021/22. [PDF]
Düking P +4 more
europepmc +1 more source
Technology development in the country with the revision of engineering courses curriculum
Attention to innovation and technology are important factors in increasing a countny,s economic growth and competitiveness. There is no doubt that science and technology are the most basic elements of economic development, and successful countries are ...
firooz bakhtiari nejad , Nahid Sheikhan
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ultra-short-term wind power prediction method combining financial technology feature engineering and XGBoost algorithm. [PDF]
Guan S +5 more
europepmc +1 more source
This study aims to determine the feasibility of mathematical modules with STEM approach and the response of learners and teachers to the attractiveness of the module.
Taza Nur Utami +2 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Among airlines and aircraft manufacturers there is much attention for passenger experience. However, there is not much literature on how the activities of passengers can be supported by the aircraft interior. The current study focuses on the need finding
Golnoosh Torkashvand +2 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

